AePONA provided the software engine that powers the “Network as a Service” (NaaS) business model for mobile operators.

Altana AI created the world’s first value chain management system to help governments and enterprises build safer, more transparent, and resilient global supply networks.

Bellco was a pioneer in haemodialysis, they were acquired by Medtronic in 2016.

Ciphergen Biosystems developed a patented protein chip to detect proteins within biological samples. The company successfully floated on NASDAQ.

Constructive Bio is a synthetic biology company that rewrites genomes to create novel biomolecules, enabling next-generation materials and therapeutics beyond the limits of natural biology.

ContactEngine was a Conversational AI company that used advanced linguistics and intent analysis to automate and optimise customer engagement across digital channels. It was acquired by Nice Systems in 2021.

Creditas is a Latin American fintech platform using proprietary technology to deliver secured loans, insurance, and investment products at scale.

Cryptosense provided cryptography management software that gave enterprises deep visibility into encryption practices, helping secure critical data across applications and infrastructure. Acquired by SandboxAQ in 2022.

CSR was a Bluetooth semiconductor pioneer whose single-chip wireless solutions brought short-range connectivity to the mass market. CSR completed an IPO and was later acquired by Qualcomm.

Descomplica is Brazil’s leading digital education platform, offering fully online degrees and career-focused learning to millions through its innovative, video-first model.

Doctify is a healthtech platform providing SaaS tools and booking services that connect patients with private healthcare providers, making access to care faster, simpler, and more transparent.

Element 14 was a fabless semiconductor company that developed chips to enable the rapid expansion of broadband connectivity. It was acquired by Broadcom for $642m in 2000.

Entropic Inc. was a speech recognition pioneer whose signal processing software and HMM innovations laid the groundwork for modern voice systems. It was acquired by Microsoft in 1999.

Epoch Biodesign is a synthetic biology company that has developed enzymes to convert unrecyclable plastic waste into valuable, low-carbon chemicals using AI and advanced automation.

FiveAI was an autonomous vehicle software company developing AI-driven systems for safe, self-driving urban transport across Europe. It was acquired by Bosch in 2022.

Healx is a Cambridge-based biotech using generative AI to accelerate drug discovery and develop treatments for rare diseases that currently lack approved therapies.

Icera was a semiconductor innovator whose software-defined modems powered next-generation mobile devices and helped redefine wireless performance. It was acquired by NVIDIA in 2011.

Igenomix is a reproductive genetics company providing advanced diagnostic testing to improve fertility outcomes and support women’s health globally. It was acquired by EQT in 2019.

iPronics is a Spanish deep tech company pioneering software-defined photonics with the world’s first programmable optical switch, enabling scalable, low-power communication for AI and data centre infrastructure.

Natrox® is an advanced wound care therapy developed in Cambridge that delivers continuous topical oxygen to accelerate healing in acute and chronic wounds.

Nu Quantum is a Cambridge spin-out developing quantum networking hardware to interconnect QPUs, enabling the scalable, multi-core quantum computers of the future.

Nuclera is a biotech company making proteins more accessible through its benchtop eProtein Discovery™ system, combining cell-free synthesis and digital microfluidics for rapid, automated protein production.

Openbravo was a cloud-based retail software company enabling agile, unified commerce experiences for retailers and restaurants worldwide. It was acquired by DL Software in 2022.

Optos was a medtech company whose Optomap imaging technology enabled early detection of retinal diseases through non-invasive, wide-field digital scans. It listed on the London Stock Exchange in 2006 and was acquired by Nikon for $400m in 2015.

OrganOx is a medtech company pioneering normothermic liver perfusion with its metra device, improving transplant outcomes and increasing the use of donor organs worldwide.

Ori Biotech is a cell and gene therapy manufacturing company whose IRO® platform automates and accelerates production to make advanced therapies more scalable, affordable, and accessible.

Oxford Nanopore Technologies develops scalable, real-time DNA/RNA sequencing tools that enable fast, accessible analysis across research, healthcare, and global diagnostics.

Paragraf is a graphene electronics company pioneering mass production of graphene-based devices to transform semiconductor performance across sectors from automotive to healthcare.

PhoreMost is a biotech company expanding the potential of targeted protein degradation through novel mini-protein engineering and proprietary platforms to develop next-generation degrader therapies.

Photonic is building a scalable, fault-tolerant quantum computer using a unique silicon spin–photon architecture that combines quantum memory with photonic connectivity.

Pimloc is an AI company specialising in video redaction and visual data privacy, helping organisations automate compliance while safely unlocking the value of real-world footage.

PolyAI develops voice-first AI agents that deliver human-level customer service at scale, helping global enterprises automate support, reduce wait times, and enhance user experience.

Quibim is a medtech company turning imaging data into predictive insights to drive precision medicine in oncology, neurology, and immunology.

Ravelin is a fraud prevention platform that uses machine learning and graph-based analysis to detect and stop fraud before it happens. It was acquired by Worldpay in 2025.

Refute is a threat intelligence platform using data-driven methods to detect and disrupt disinformation campaigns targeting businesses, institutions, and society at large.

Riverlane is a quantum computing company developing Deltaflow, a Quantum Error Correction Stack that enables quantum computers to scale and deliver real-world impact sooner.

RoboK is a Cambridge-based computer vision start-up using AI to turn industrial CCTV data into actionable insights for safer, high-performing workplaces.

Safe Intelligence is a deep tech spin-out from Imperial College London developing scalable AI validation tools to ensure the safe and reliable deployment of machine learning models.

SandboxAQ is an enterprise software company combining AI and quantum technologies to solve major challenges across healthcare, finance, cybersecurity, and navigation.

Secondmind is the provider of the world's first AI-powered decision-making platform, helping automotive engineers design better cars, faster.

Seldon is a machine learning infrastructure company enabling scalable, production-grade model deployment through its open-source platform, Seldon Core.

Sitehop is a UK-based cybersecurity company delivering FPGA-powered, quantum-ready encryption with sub-microsecond latency and ultra-low power consumption to protect data in motion across global networks.

SLAMcore is a Spatial AI company providing real-time localisation and mapping software that enables robots to understand and interact with the world around them.

Solexa developed next-generation genome sequencing technology to make high-speed, low-cost DNA analysis accessible for research and clinical diagnostics. It was acquired by Illumina in 2007.

Sprout.ai uses AI and deep search technology to automate and accelerate insurance claims by generating accurate, data-rich insights in real time.

Tenzo is a machine learning-powered analytics and forecasting platform that helps restaurants unify their data and make faster, smarter operational decisions in real time.

Tobii is the global leader in remote eye tracking, developing technology that powers next-generation human-machine interaction across consumer and professional applications. The company listed on Nasdaq Stockholm in 2015.

Transmode delivered optical networking solutions using CWDM and DWDM technologies to help telecom operators expand network capacity and performance efficiently. It listed on Stockholm NASDAQ OMX in 2011 and was acquired by Infinera in 2015.

Unlikely AI is a London-based company pioneering neurosymbolic AI that combines the power of machine learning with the reliability of symbolic computing to deliver trustworthy, explainable, next-generation AI systems.

V7 builds Trustworthy AI systems that combine human insight with foundation models to deliver scalable, vision-powered automation across critical industries.

VocalIQ was a Cambridge-based voice AI start-up developing adaptive, learning-based spoken language systems. It was acquired in 2015 by Apple to strengthen its conversational interface technology.

Xampla is a Cambridge-based materials science company pioneering plant protein-based alternatives to single-use plastics.

XMOS is a UK-based fabless semiconductor company enabling software-defined, customisable SoC solutions for voice and embedded applications.

XYZ Reality is a construction tech company combining engineering-grade AR with a real-time delivery platform, giving teams full project visibility and the tools to build faster, safer, and with unmatched precision.